Morecambe went down to their first defeat in five games after a freak goal gave Orient the points in the first ever meeting between the two sides.
A tight game was won by Jack Payne’s 29th minute fluke with the normally free scoring Shrimps unable to get their way back into the game.
Jim Bentley was forced to leave out the in-form Shaun Miller and his absence told as Shrimps, who started the day as the Football League’s top scorers, failed to score for the first time in seven games.
Morecambe had the better of the encounters with Ryan Edwards and Jamie Devitt heading decent opportunities wide before the game’s decisive moment just before the half hour.
Payne beat his marker and tried to pass to his team mate, but the ball got intercepted and Edwards attempted clearance was charged down by the Orient midfielder and flew past Barry Roche in the Morecambe goal and into the net.
It was his first goal for the club and hit the Shrimps’ confidence. Kevin Ellison tried to spark his side back into life with a curler from the edge of the box but Alex Cisak saved smartly to his left.
The O’s pushed to extend their lead and broke smartly seven minutes before the interval after Palmer won the ball off the home defence. He passed out to Bradley Pritchard on the right hand side and his cross looped over Roche, but hit the crossbar and bounced over.
The Shrimps had a great chance to level in the opening minute of the second half. Devitt played in Paul Mullin with a superb through ball but after the young striker cut inside Connor Essam he curled a poor effort wide of the left hand post.
Orient then went close to extending their lead in the 49th minute when Ollie Palmer won Pritchard’s centre, but Jay Simpson poked wide at the far post at full stretch.
Simpson went close again minutes later when the former Arsenal man showed his quality with a superb turn and shot from the edge of the area that flew inches wide of the right hand post.
From there, however, the game was dominated by the Shrimps. A Devitt corner was won by Alan Goodall but he couldn’t get over the top of the ball and his effort went over.
The busy Devitt then drilled an effort wide from the edge of the box and Aaron Wildig, a second half substitute, tested Cisak for one of the first times in the game when he let fly from range.
Wildig was starting to become more and more influential and he teed up Tom Barkhuizen perfectly with a pinpoint cross from the left but the young striker failed t make contact with the ball.
The Shrimps continued to pile on the pressure pressure and Barkhuizen forced Cisak into a stunning low with a smart effort from 12 yards out before the Shrimps were denied a penalty when O’s captain Mathieu Baudry appeared to handle the ball in the area but the appeals were waved away and Morecambe suffered their fourth home defeat in five games at the Globe.
MORECAMBE: Roche, Beeley, McGowan, Kenyon (Kelleher 81), Edwards, Devitt, Barkhuizen, Ellison, Mullin (Molyneux 68), Goodall (Wildig 59), Parrish. Unused substitutes: Thompson, Bondswell, Bailey.
LEYTON ORIENT: Leyton Orient: Cisak, Clohessy, Baudry, Essam, Chicksen, Payne, Pritchard, Moore, Marquis (James 63), Simpson (Turgott 87), Palmer. Unused substitutes: Grainger, Shaw, Dunne, Kashket, Moncur.