The Shrimps got their first win of the new Checkatrade Trophy competition with victory over 10-man Stoke City.
Jack Dunn, Cole Stockton and Peter Murphy all scored in the opening period to effectively end the match as a contest by half-time.
Charlie Adam pulled one back from distance early in the second half as the Shrimps somewhat stuttered after the break.
They ended with 10 men as well, though in their case, it was down to losing Aaron Wildig, Ryan Edwards, Alex Kenyon and Dean Winnard to injury.
It was on a stretcher in the latter’s case, having appeared to injure his groin.
It was certainly an evening to forget for Stoke’s Liam Edwards who was at fault for the opening goal and was sent off on the quarter-hour.
With most inside the Globe Arena digesting some unfamiliar faces in the visitors’ camp, the Shrimps quickly took a third minute lead.
Dunn capitalised on a horrendous error from Liam Edwards to finish confidently past Jakob Haugaard.
The woodwork kept out Adam’s free kick before the game changed completely moments later when Liam Edwards was sent off for an awful challenge on Wildig.
It wasn’t the last rough challenge on the Shrimps’ midfielder before half-time, though two others resulted in goals.
Adam’s late challenge on Wildog didn’t prevent Stockton from getting the better of the defence to slot past Haugaard.
Then, with half-time approaching, Haugaard clattered into Wildig in trying to cut out Aaron McGowan’s ball forward, only for Murphy to tap into an empty net.
In contrast, the second half was one where the visitors enjoyed greater dominance.
Adam pulled a goal back from 25 yards three minutes into the second half and continued to chance his arm from distance thereafter.
Danijel Nizic turned an Oliver Shenton shot behind and Mame Biram Diouf headed off target as the half became increasingly fractious with the home side unhappy at some of the visitors’ challenges.
Dunn and Stockton were off target for the Shrimps, though there was still time for Stoke’s Phil Bardsley to twice fire off target from distance as, despite six minutes’ added time, Jim Bentley’s men claimed victory.
Morecambe: Nizic, Ryan Edwards (Barkhuizen 54), Winnard, Whitmore, McGowan, Murphy, Kenyon (Rose 69), Wildig (Turner 48), Molyneux, Dunn, Stockton. Not used: Roche, Wakefield, Mullin, Massanka.
Stoke City: Haugaard, Bardsley, Liam Edwards, Muniesa, Renee-Pringle, Molina, Adam, Taylor, Ngoy, Diouf, Shenton (Telford 72). Not used: Jarvis, Isted, Sweeney, Waddington.
Referee: Andy Haines